P63S (p.Pro63Ser) variant of CYP2C8 (Cytochrome P450 2C8)
P63S (p.Pro63Ser) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
P63S (p.Pro63Ser) variant details
- p.Pro63Ser
- ExAC rs777455799
- TOPMed rs777455799
- gnomAD rs777455799
- Missense
- Variant Prioritization Score for Impact Estimate 0.2
- REVEL 0.16
- CADD 24.60
- PolyPhen-2 0.46
- SIFT 0.05
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available