P63A (p.Pro63Ala) variant of CYP2C8 (Cytochrome P450 2C8)
P63A (p.Pro63Ala) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
P63A (p.Pro63Ala) variant details
- p.Pro63Ala
- ExAC rs777455799
- TOPMed rs777455799
- gnomAD rs777455799
- Missense
- Variant Prioritization Score for Impact Estimate 0.222
- REVEL 0.21
- CADD 22.80
- PolyPhen-2 0.44
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available