P3T (p.Pro3Thr) variant of CYP2C8 (Cytochrome P450 2C8)
P3T (p.Pro3Thr) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
P3T (p.Pro3Thr) variant details
- p.Pro3Thr
- ESP rs373001219
- ExAC rs373001219
- TOPMed rs373001219
- Missense
- Variant Prioritization Score for Impact Estimate 0.205
- REVEL 0.22
- CADD 14.80
- PolyPhen-2 0.61
- SIFT 0.22
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available