P3R (p.Pro3Arg) variant of CYP2C8 (Cytochrome P450 2C8)
P3R (p.Pro3Arg) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
P3R (p.Pro3Arg) variant details
- p.Pro3Arg
- gnomAD rs1273514910
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- REVEL 0.33
- CADD 7.45
- PolyPhen-2 0.82
- SIFT 0.04
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available