P35L (p.Pro35Leu) variant of CYP2C8 (Cytochrome P450 2C8)
P35L (p.Pro35Leu) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
P35L (p.Pro35Leu) variant details
- p.Pro35Leu
- ExAC rs775351304
- gnomAD rs775351304
- Missense
- Variant Prioritization Score for Impact Estimate 0.391
- REVEL 0.24
- CADD 24.50
- PolyPhen-2 0.74
- SIFT 0.01
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available