P33L (p.Pro33Leu) variant of CYP2C8 (Cytochrome P450 2C8)
P33L (p.Pro33Leu) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
P33L (p.Pro33Leu) variant details
- p.Pro33Leu
- gnomAD rs1400611147
- Missense
- Variant Prioritization Score for Impact Estimate 0.557
- REVEL 0.52
- CADD 25.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.4e-05)
- Structural context available