M14L (p.Met14Leu) variant of CYP2C8 (Cytochrome P450 2C8)
M14L (p.Met14Leu) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
M14L (p.Met14Leu) variant details
- p.Met14Leu
- 1000Genomes rs530027098
- ExAC rs530027098
- gnomAD rs530027098
- Missense
- Variant Prioritization Score for Impact Estimate 0.103
- REVEL 0.12
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the 1KG:GIH population (allele frequency 0.005)
- Structural context available