M14K (p.Met14Lys) variant of CYP2C8 (Cytochrome P450 2C8)
M14K (p.Met14Lys) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
M14K (p.Met14Lys) variant details
- p.Met14Lys
- TOPMed rs1187705870
- gnomAD rs1187705870
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.17
- CADD 14.00
- PolyPhen-2 0.02
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available