M1? variant of CYP2C8 (Cytochrome P450 2C8)
M1? in CYP2C8 (Cytochrome P450 2C8) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes structural context.
M1? variant details
- rs1359014715
- NCI-TCGA Cosmic COSV6487
- Variant assessed as somatic; high impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.477
- MetaLR 0.46
- MetaSVM -0.38
- PolyPhen-2 1.00
- SIFT 0.00
- MutPred 0.90
- UniProt: Variant assessed as somatic; high impact.
- Structural context available