L29H (p.Leu29His) variant of CYP2C8 (Cytochrome P450 2C8)
L29H (p.Leu29His) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
L29H (p.Leu29His) variant details
- p.Leu29His
- TOPMed rs1269726684
- gnomAD rs1269726684
- Missense
- Variant Prioritization Score for Impact Estimate 0.363
- REVEL 0.26
- CADD 22.50
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available