L19R (p.Leu19Arg) variant of CYP2C8 (Cytochrome P450 2C8)
L19R (p.Leu19Arg) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
L19R (p.Leu19Arg) variant details
- p.Leu19Arg
- gnomAD rs1270973407
- Missense
- Variant Prioritization Score for Impact Estimate 0.37
- REVEL 0.32
- CADD 15.80
- PolyPhen-2 0.38
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available