L16V (p.Leu16Val) variant of CYP2C8 (Cytochrome P450 2C8)
L16V (p.Leu16Val) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
L16V (p.Leu16Val) variant details
- p.Leu16Val
- TOPMed rs1188823438
- gnomAD rs1188823438
- Missense
- Variant Prioritization Score for Impact Estimate 0.202
- REVEL 0.05
- CADD 4.09
- PolyPhen-2 0.05
- SIFT 0.12
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available