L16P (p.Leu16Pro) variant of CYP2C8 (Cytochrome P450 2C8)
L16P (p.Leu16Pro) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
L16P (p.Leu16Pro) variant details
- p.Leu16Pro
- gnomAD rs1437372954
- Missense
- Variant Prioritization Score for Impact Estimate 0.43
- REVEL 0.42
- CADD 16.90
- PolyPhen-2 0.07
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available