L15F (p.Leu15Phe) variant of CYP2C8 (Cytochrome P450 2C8)
L15F (p.Leu15Phe) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
L15F (p.Leu15Phe) variant details
- p.Leu15Phe
- gnomAD rs1260275686
- Missense
- Variant Prioritization Score for Impact Estimate 0.193
- REVEL 0.06
- CADD 0.51
- PolyPhen-2 0.03
- SIFT 0.12
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available