K59E (p.Lys59Glu) variant of CYP2C8 (Cytochrome P450 2C8)
K59E (p.Lys59Glu) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
K59E (p.Lys59Glu) variant details
- p.Lys59Glu
- TOPMed rs1355198251
- gnomAD rs1355198251
- Missense
- Variant Prioritization Score for Impact Estimate 0.231
- REVEL 0.14
- CADD 5.28
- PolyPhen-2 0.01
- SIFT 0.53
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available