K108N (p.Lys108Asn) variant of CYP2C8 (Cytochrome P450 2C8)
K108N (p.Lys108Asn) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
K108N (p.Lys108Asn) variant details
- p.Lys108Asn
- 1000Genomes rs188305680
- ExAC rs188305680
- TOPMed rs188305680
- gnomAD rs188305680
- Missense
- Variant Prioritization Score for Impact Estimate 0.197
- REVEL 0.11
- CADD 0.11
- PolyPhen-2 0.02
- SIFT 0.32
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available