I88T (p.Ile88Thr) variant of CYP2C8 (Cytochrome P450 2C8)
I88T (p.Ile88Thr) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
I88T (p.Ile88Thr) variant details
- p.Ile88Thr
- 1000Genomes rs201449274
- ExAC rs201449274
- TOPMed rs201449274
- gnomAD rs201449274
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.15
- CADD 18.50
- PolyPhen-2 0.23
- SIFT 0.02
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available