I88S (p.Ile88Ser) variant of CYP2C8 (Cytochrome P450 2C8)
I88S (p.Ile88Ser) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
I88S (p.Ile88Ser) variant details
- p.Ile88Ser
- 1000Genomes rs201449274
- ExAC rs201449274
- TOPMed rs201449274
- gnomAD rs201449274
- Missense
- Variant Prioritization Score for Impact Estimate 0.414
- REVEL 0.34
- CADD 22.90
- PolyPhen-2 0.77
- SIFT 0.00
- Most common in the East Asian population (allele frequency 0.0001)
- Structural context available