I50T (p.Ile50Thr) variant of CYP2C8 (Cytochrome P450 2C8)
I50T (p.Ile50Thr) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
I50T (p.Ile50Thr) variant details
- p.Ile50Thr
- ESP rs375170154
- TOPMed rs375170154
- gnomAD rs375170154
- Missense
- Variant Prioritization Score for Impact Estimate 0.157
- REVEL 0.13
- CADD 16.80
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available