I102V (p.Ile102Val) variant of CYP2C8 (Cytochrome P450 2C8)
I102V (p.Ile102Val) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
I102V (p.Ile102Val) variant details
- p.Ile102Val
- ExAC rs780189252
- TOPMed rs780189252
- gnomAD rs780189252
- Missense
- Variant Prioritization Score for Impact Estimate 0.0672
- REVEL 0.06
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Middle Eastern population (allele frequency 0.00087)
- Structural context available