H78R (p.His78Arg) variant of CYP2C8 (Cytochrome P450 2C8)
H78R (p.His78Arg) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
H78R (p.His78Arg) variant details
- p.His78Arg
- ExAC rs761964694
- gnomAD rs761964694
- Missense
- Variant Prioritization Score for Impact Estimate 0.307
- REVEL 0.16
- CADD 22.40
- PolyPhen-2 0.86
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available