G117A (p.Gly117Ala) variant of CYP2C8 (Cytochrome P450 2C8)
G117A (p.Gly117Ala) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
G117A (p.Gly117Ala) variant details
- p.Gly117Ala
- TOPMed rs1455733744
- gnomAD rs1455733744
- Missense
- Variant Prioritization Score for Impact Estimate 0.331
- REVEL 0.16
- CADD 20.40
- Most common in the African/African-American population (allele frequency 5e-05)
- Structural context available