G109A (p.Gly109Ala) variant of CYP2C8 (Cytochrome P450 2C8)
G109A (p.Gly109Ala) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
G109A (p.Gly109Ala) variant details
- p.Gly109Ala
- Ensembl rs2033597547
- Missense
- Variant Prioritization Score for Impact Estimate 0.0859
- REVEL 0.07
- CADD 6.21
- PolyPhen-2 0.19
- SIFT 0.01
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available