F77V (p.Phe77Val) variant of CYP2C8 (Cytochrome P450 2C8)
F77V (p.Phe77Val) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
F77V (p.Phe77Val) variant details
- p.Phe77Val
- TOPMed rs1407175407
- gnomAD rs1407175407
- Missense
- Variant Prioritization Score for Impact Estimate 0.264
- REVEL 0.18
- CADD 8.62
- PolyPhen-2 0.00
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available