F57L (p.Phe57Leu) variant of CYP2C8 (Cytochrome P450 2C8)
F57L (p.Phe57Leu) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
F57L (p.Phe57Leu) variant details
- p.Phe57Leu
- ExAC rs747486167
- gnomAD rs747486167
- Missense
- Variant Prioritization Score for Impact Estimate 0.0799
- REVEL 0.08
- CADD 0.01
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available