F4S (p.Phe4Ser) variant of CYP2C8 (Cytochrome P450 2C8)
F4S (p.Phe4Ser) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
F4S (p.Phe4Ser) variant details
- p.Phe4Ser
- TOPMed rs1230631165
- gnomAD rs1230631165
- Missense
- Variant Prioritization Score for Impact Estimate 0.163
- REVEL 0.05
- CADD 1.69
- PolyPhen-2 0.01
- SIFT 0.15
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available