E85G (p.Glu85Gly) variant of CYP2C8 (Cytochrome P450 2C8)
E85G (p.Glu85Gly) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
E85G (p.Glu85Gly) variant details
- p.Glu85Gly
- ExAC rs776037747
- TOPMed rs776037747
- gnomAD rs776037747
- Missense
- Variant Prioritization Score for Impact Estimate 0.681
- REVEL 0.77
- CADD 28.10
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available