D89N (p.Asp89Asn) variant of CYP2C8 (Cytochrome P450 2C8)
D89N (p.Asp89Asn) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
D89N (p.Asp89Asn) variant details
- p.Asp89Asn
- cosmic curated COSV10652
- TOPMed rs1465803140
- gnomAD rs1465803140
- Missense
- Variant Prioritization Score for Impact Estimate 0.356
- REVEL 0.21
- CADD 20.30
- PolyPhen-2 0.26
- SIFT 0.04
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available