D46N (p.Asp46Asn) variant of CYP2C8 (Cytochrome P450 2C8)
D46N (p.Asp46Asn) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
D46N (p.Asp46Asn) variant details
- p.Asp46Asn
- Ensembl rs1589450506
- Missense
- Variant Prioritization Score for Impact Estimate 0.093
- REVEL 0.11
- CADD 0.34
- PolyPhen-2 0.01
- SIFT 0.47
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available