C10R (p.Cys10Arg) variant of CYP2C8 (Cytochrome P450 2C8)
C10R (p.Cys10Arg) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
C10R (p.Cys10Arg) variant details
- p.Cys10Arg
- gnomAD rs1351448178
- Missense
- Variant Prioritization Score for Impact Estimate 0.404
- REVEL 0.35
- CADD 18.60
- PolyPhen-2 0.64
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available