A86V (p.Ala86Val) variant of CYP2C8 (Cytochrome P450 2C8)
A86V (p.Ala86Val) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
A86V (p.Ala86Val) variant details
- p.Ala86Val
- TOPMed rs1281410078
- Missense
- Variant Prioritization Score for Impact Estimate 0.414
- REVEL 0.30
- CADD 21.80
- PolyPhen-2 0.61
- SIFT 0.08
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available