A86T (p.Ala86Thr) variant of CYP2C8 (Cytochrome P450 2C8)
A86T (p.Ala86Thr) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
A86T (p.Ala86Thr) variant details
- p.Ala86Thr
- gnomAD rs1369026893
- Missense
- Variant Prioritization Score for Impact Estimate 0.604
- REVEL 0.62
- CADD 23.20
- PolyPhen-2 0.81
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 6.4e-05)
- Structural context available