A82T (p.Ala82Thr) variant of CYP2C8 (Cytochrome P450 2C8)
A82T (p.Ala82Thr) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
A82T (p.Ala82Thr) variant details
- p.Ala82Thr
- 1000Genomes rs17851796
- ExAC rs17851796
- TOPMed rs17851796
- gnomAD rs17851796
- Missense
- Variant Prioritization Score for Impact Estimate 0.156
- REVEL 0.14
- CADD 15.70
- PolyPhen-2 0.04
- SIFT 0.02
- Most common in the 1KG:CHB population (allele frequency 0.0049)
- Structural context available