A82S (p.Ala82Ser) variant of CYP2C8 (Cytochrome P450 2C8)
A82S (p.Ala82Ser) in CYP2C8 (Cytochrome P450 2C8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
A82S (p.Ala82Ser) variant details
- p.Ala82Ser
- 1000Genomes rs17851796
- ExAC rs17851796
- TOPMed rs17851796
- gnomAD rs17851796
- Missense
- Variant Prioritization Score for Impact Estimate 0.195
- REVEL 0.21
- CADD 15.00
- PolyPhen-2 0.24
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available