V8V (p.Val8Val) variant of CYP2C19 (Cytochrome P450 2C19)
V8V (p.Val8Val) in CYP2C19 (Cytochrome P450 2C19) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
V8V (p.Val8Val) variant details
- p.Val8Val
- rs779012951
- gnomAD 10-94762729-G-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.397
- CADD 1.49
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 0.791
- Literature evidence available