V50V (p.Val50Val) variant of CYP2C19 (Cytochrome P450 2C19)
V50V (p.Val50Val) in CYP2C19 (Cytochrome P450 2C19) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
V50V (p.Val50Val) variant details
- p.Val50Val
- gnomAD 10-94762855-C-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.397
- CADD 1.22
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available
- CYP2C19 VAMP-seq synonymous scores: score 1.04
- Literature evidence available