V38M (p.Val38Met) variant of CYP2C19 (Cytochrome P450 2C19)
V38M (p.Val38Met) in CYP2C19 (Cytochrome P450 2C19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, experimental measurements, and structural context.
V38M (p.Val38Met) variant details
- p.Val38Met
- cosmic curated COSV64907
- ExAC rs754931221
- gnomAD rs754931221
- Missense
- Variant Prioritization Score for Impact Estimate 0.135
- REVEL 0.10
- MetaLR 0.21
- MetaSVM -0.82
- CADD 7.20
- PolyPhen-2 0.31
- SIFT 0.00
- Most common in the HGDP:BIAKA population (allele frequency 0.93)
- Structural context available
- CYP2C19 VAMP-seq synonymous scores: score 0.939