T34R (p.Thr34Arg) variant of CYP2C19 (Cytochrome P450 2C19)
T34R (p.Thr34Arg) in CYP2C19 (Cytochrome P450 2C19) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
T34R (p.Thr34Arg) variant details
- p.Thr34Arg
- gnomAD 10-94762805-A-AGG
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.193
- CADD 15.80
- Population evidence available
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 0.953
- Literature evidence available