T34I (p.Thr34Ile) variant of CYP2C19 (Cytochrome P450 2C19)
T34I (p.Thr34Ile) in CYP2C19 (Cytochrome P450 2C19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, experimental measurements, and structural context.
T34I (p.Thr34Ile) variant details
- p.Thr34Ile
- Ensembl rs1848190307
- Missense
- Variant Prioritization Score for Impact Estimate 0.0968
- REVEL 0.06
- MetaLR 0.04
- MetaSVM -0.98
- CADD 5.22
- PolyPhen-2 0.13
- SIFT 0.25
- Population evidence available
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 0.953