S51N (p.Ser51Asn) variant of CYP2C19 (Cytochrome P450 2C19)
S51N (p.Ser51Asn) in CYP2C19 (Cytochrome P450 2C19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, experimental measurements, and structural context.
S51N (p.Ser51Asn) variant details
- p.Ser51Asn
- Ensembl rs1848191638
- Missense
- Variant Prioritization Score for Impact Estimate 0.0839
- REVEL 0.02
- MetaLR 0.02
- MetaSVM -0.99
- CADD 6.86
- PolyPhen-2 0.01
- SIFT 0.41
- Population evidence available
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 0.601