S51G (p.Ser51Gly) variant of CYP2C19 (Cytochrome P450 2C19)
S51G (p.Ser51Gly) in CYP2C19 (Cytochrome P450 2C19) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as drug response in the context of Voriconazole response; Citalopram response; Sertraline response. The record also includes experimental measurements, published literature, and structural context.
S51G (p.Ser51Gly) variant details
- p.Ser51Gly
- rs1564657013
- ClinVar RCV000783651
- UniProt VAR 024083
- Ensembl rs1564657013
- drug response
- Voriconazole response; Citalopram response; Sertraline response
- Missense
- ClinVar: drug response (Voriconazole response; Citalopram response; Sertraline response)
- EBI: Benign (in allele CYP2C19*19)
- UniProt: Benign (in allele CYP2C19*19)
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 0.601
- Cited in: Genetic variations and haplotypes of CYP2C19 in a Japanese population. (PMID 16141610)