S24P (p.Ser24Pro) variant of CYP2C19 (Cytochrome P450 2C19)
S24P (p.Ser24Pro) in CYP2C19 (Cytochrome P450 2C19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S24P (p.Ser24Pro) variant details
- p.Ser24Pro
- gnomAD 10-94762775-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.217
- REVEL 0.09
- MetaLR 0.17
- MetaSVM -1.00
- CADD 6.43
- PolyPhen-2 0.09
- SIFT 0.21
- Population evidence available
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 0.938
- Literature evidence available