S24C (p.Ser24Cys) variant of CYP2C19 (Cytochrome P450 2C19)
S24C (p.Ser24Cys) in CYP2C19 (Cytochrome P450 2C19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S24C (p.Ser24Cys) variant details
- p.Ser24Cys
- gnomAD 10-94762776-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.117
- REVEL 0.08
- MetaLR 0.19
- MetaSVM -1.01
- CADD 4.84
- PolyPhen-2 0.13
- SIFT 0.15
- Population evidence available
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 0.938
- Literature evidence available