S23S (p.Ser23Ser) variant of CYP2C19 (Cytochrome P450 2C19)
S23S (p.Ser23Ser) in CYP2C19 (Cytochrome P450 2C19) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S23S (p.Ser23Ser) variant details
- p.Ser23Ser
- rs1321377551
- gnomAD 10-94762774-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.083
- CADD 0.34
- Most common in the 1KG:GIH population (allele frequency 0.0053)
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 0.96
- Literature evidence available