S12S (p.Ser12Ser) variant of CYP2C19 (Cytochrome P450 2C19)
S12S (p.Ser12Ser) in CYP2C19 (Cytochrome P450 2C19) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S12S (p.Ser12Ser) variant details
- p.Ser12Ser
- rs1202106669
- gnomAD 10-94762741-A-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.136
- CADD 7.81
- Population evidence available
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 0.823
- Literature evidence available