R26S (p.Arg26Ser) variant of CYP2C19 (Cytochrome P450 2C19)
R26S (p.Arg26Ser) in CYP2C19 (Cytochrome P450 2C19) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
R26S (p.Arg26Ser) variant details
- p.Arg26Ser
- gnomAD 10-94762782-GAGGA
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.556
- CADD 19.90
- Population evidence available
- Structural context available
- CYP2C19 VAMP-seq synonymous scores: score 0.926
- Literature evidence available