Q22Q (p.Gln22Gln) variant of CYP2C19 (Cytochrome P450 2C19)
Q22Q (p.Gln22Gln) in CYP2C19 (Cytochrome P450 2C19) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
Q22Q (p.Gln22Gln) variant details
- p.Gln22Gln
- rs774043444
- gnomAD 10-94762771-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0835
- CADD 0.40
- Most common in the African/African-American population (allele frequency 2.8e-05)
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 1.07
- Literature evidence available