P37S (p.Pro37Ser) variant of CYP2C19 (Cytochrome P450 2C19)
P37S (p.Pro37Ser) in CYP2C19 (Cytochrome P450 2C19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
P37S (p.Pro37Ser) variant details
- p.Pro37Ser
- gnomAD 10-94762814-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.342
- REVEL 0.22
- MetaLR 0.20
- MetaSVM -0.55
- CADD 18.00
- PolyPhen-2 0.89
- SIFT 0.02
- Population evidence available
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 0.306
- Literature evidence available