P33P (p.Pro33Pro) variant of CYP2C19 (Cytochrome P450 2C19)
P33P (p.Pro33Pro) in CYP2C19 (Cytochrome P450 2C19) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
P33P (p.Pro33Pro) variant details
- p.Pro33Pro
- rs17885098
- gnomAD 10-94762804-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.393
- CADD 0.58
- Population evidence available
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 0.111
- Cited in: Gene-environment interactions between air pollution and biotransformation enzymes and risk of birth defects. (PMID 33569925)
- Cited in: Genetic Diversity of Drug-Related Genes in Native Americans of the Brazilian Amazon. (PMID 33519226)