P31W (p.Pro31Trp) variant of CYP2C19 (Cytochrome P450 2C19)
P31W (p.Pro31Trp) in CYP2C19 (Cytochrome P450 2C19) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
P31W (p.Pro31Trp) variant details
- p.Pro31Trp
- gnomAD 10-94762795-TCC-T
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.227
- CADD 20.70
- Population evidence available
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 0.428
- Literature evidence available